[HTML][HTML] Metabolic fingerprinting of bacteria by fluorescence lifetime imaging microscopy

A Bhattacharjee, R Datta, E Gratton, AI Hochbaum - Scientific reports, 2017 - nature.com
… The identification of bacterial metabolic states and transitions between them in … fluorescence
lifetime imaging microscopy (FLIM) to create a metabolic fingerprint of individual bacteria

Fluorescence Lifetime Imaging Microscopy of Porphyrins in Helicobacter pylori Biofilms

A Battisti, P Morici, A Sgarbossa - Pharmaceutics, 2021 - mdpi.com
… in the image to a point in the phasor plot [15]. The FLIM-phasor approach has been used to
… a metabolic fingerprint of individual bacteria and pop-ulations by monitoring the lifetime of …

Fluorescence lifetime imaging microscopy (FLIM): a non-traditional approach to study host-microbial symbioses

P Deore, I Wanigasuriya, SJTM Ching… - Microbiology …, 2022 - CSIRO Publishing
… ) coupled with fluorescence lifetime imaging microscopy (FLIM… in situ location and identity
of bacteria in Symbiodiniaceae. … endogenous chemicals (eg metabolic co-enzymes, structural …

Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy

DH Lee, X Li, N Ma, MA Digman, AP Lee - Lab on a Chip, 2018 - pubs.rsc.org
… an indirect measurement of metabolic alteration in living cells… by mapping their metabolic
fingerprints without any labeling … neutrophil count caused by bacterial infections often cause an …

A rapid analysis platform for investigating the cellular locations of bacteria using two-photon fluorescence lifetime imaging microscopy

N Sapermsap, DDU Li, R Al-Hemedawi… - … in Fluorescence, 2020 - iopscience.iop.org
… , a red-fluorescent by-product of bacterial haem production, and … Most interestingly, two-photon
FLIM imaging of the metabolic … been used for bacterial metabolic fingerprinting in diverse …

[HTML][HTML] Machine learning methods for fluorescence lifetime imaging (FLIM) based label-free detection of microglia

MAK Sagar, KP Cheng, JN Ouellette… - Frontiers in …, 2020 - frontiersin.org
… can be estimated instantly without the time-consuming exponential curve fitting); and (ii)
possibly identify an optical/metabolic fingerprint which would otherwise not be apparent with …

[HTML][HTML] Microglia activation visualization via fluorescence lifetime imaging microscopy of intrinsically fluorescent metabolic cofactors

MAK Sagar, JN Ouellette, KP Cheng… - …, 2020 - spiedigitallibrary.org
… free signatures for different cell types ranging from bacteria to stem cells. A strategy reported
… that mean NADH lifetime is well-suited for identifying a microglial fingerprint upon activation. …

[图书][B] Label-free fluorescence lifetime imaging microscopy (FLIM) to study metabolism and oxidative stress in biological systems

R Datta - 2016 - search.proquest.com
fluorescence lifetime imaging microscopy (FLIM) of intrinsic fluorophores for label-free metabolic
and oxidative stress imaging … FLIM-phasor fingerprint of clinically important bacteria. We …

[HTML][HTML] Fluorescence Lifetime Imaging Unravels C. trachomatis Metabolism and Its Crosstalk with the Host Cell

M Szaszák, P Steven, K Shima… - PLoS …, 2011 - journals.plos.org
metabolism in intracellular bacterial infections that exceeds sole competition for nutrients. In
conclusion, fluorescence lifetime imaging … with host cell metabolism, metabolic profiling of …

[HTML][HTML] Raman imaging and fluorescence lifetime imaging microscopy for diagnosis of cancer state and metabolic monitoring

L Becker, N Janssen, SL Layland, TE Mürdter, AT Nies… - Cancers, 2021 - mdpi.com
… -active [8] and thus provide molecular fingerprints that are highly sensitive and can reflect a
… modalities of these techniques for cancer imaging, metabolic monitoring, and diagnosis. In …